When it seems that all methods of infertility treatment have failed, the last chance for having a baby is in vitro with the donor eggs of the anonymous donor. However, the issue of adopting oocytes raises a lot of questions and doubts. Rightly?
We continue our talk about the adoption of oocytes and in vitro with the donor's eggs with MD PhD Dariusz Mercik, a gynecologist and specialist in infertility treatment at the Gyncentrum Infertility Clinic.
How the in vitro with the donor eggs is performed in women who cannot have a child because of a cancer?
Patients who have lost fertility as a result of the disease and cancer therapy can use the donor's eggs and undergo the procedure of in vitro fertilization. Of course, if embryo transfer is possible and there are no medical contraindications for the patient to get pregnant. The women who are affected by this problem are most often perfectly aware of the topic and want to take advantage of this opportunity. In these cases, we usually do not try other methods of treatment. If woman has high FSH, low estradiol and very low AMH, and is aware of the fact that adoption of oocytes is the only way for her to have a child, we immediately proceed the procedure of oocyte adoption.
Can any woman undergo donation in vitro with a donor's eggs? What are the contraindications?
As a rule, contraindications to the in vitro procedure with the donor eggs are the same as in the case of traditional in vitro. These include cases in which we are unable to perform the embryo transfer in woman, i.e. uterine defects that prevent the implementing of the embryo and the proper development of pregnancy, as well as severe diseases that are contraindications to pregnancy.
How does the selection of donor eggs looks like? Does a couple who decides to adopt oocytes choose a specific donor's eggs, e.g. a friend?
The doctor, when choosing the donor, takes into account the similarity of the phenotypic and morphological features. The Polish law guarantees full anonymity of both the recipient and the donor of oocytes. The legislator provided only anonymous donation and reproductive eggs. Patients cannot, therefore, indicate a specific woman as a donor.
What criteria must be met by a candidate for a donor? What is the preparation and stimulation of the donor of ova is?
A candidate for a donor has to meet certain criteria and has to undergo a multi-stage qualification procedure in our clinic. Ladies who want to join the oocyte donation program must be no less than 20 and not more than 32 years old, be in good health and have no addictions. The candidate must also perform a number of genetic and virological tests (HIV, hepatitis B and C, syphilis, HTLV). Only positive verification, lack of genetic burden and negative results of virological tests qualifie for the program. Then the donor is subjected to hormonal stimulation to induce multiple ovulation. Stimulation involves taking hormonal medicines in the form of injections. After about 10 days, ovarian puncture is performed, when the oocytes are collected.
Have you noticed, over the years, a change in the approach of Polish patients to in vitro and the adoption of oocytes?
I must admit that I notice a big change in the attitude of Poles to such procedures in recent years. Patients now have unlimited access to information. They are more aware and more willing to use the possibilities offered by modern medicine. With Polish patients I usually meet at the very beginning of their path, eg. at the stage of diagnosing reasons of infertility. Then we go through the next stages of treatment until we reach the point where we have to decide what to do next. For most couples, however, they are not an obstacle to continuing treatment and decision to adopt a donor's eggs. Another group of patients are foreigners, who are treated in the Gyncentrum Clinic.These patient's history of infertility treatment usually includes unsuccessful IVF procedures. Usually 99% Patients arriving to our clinic are determine to adopt oocytes and their concerns are less. Throughout my career I have not had a single pair that would undergo an in-vitro procedure with the donor's eggs, get pregnant and return to me dissatisfied. These patients feel 100% parent of the child and have no doubts about it.